- Title
- Evidence supporting zoonotic transmission of Cryptosporidium in rural New South Wales
- Creator
- Ng, Josephine; Eastwood, Keith; Durrheim, David; Massey, Peter; Walker, Belinda; Armson, Anthony; Ryan, Una
- Relation
- Experimental Parasitology Vol. 119, Issue 1, p. 192-195
- Publisher Link
- http://dx.doi.org/10.1016/j.exppara.2008.01.010
- Publisher
- Academic Press
- Resource Type
- journal article
- Date
- 2008
- Description
- Cryptosporidium hominis, which has an anthroponotic transmission cycle and Cryptosporidium parvum, which is zoonotic, are the primary species of Cryptosporidium that infect humans. The present study identified the species/genotypes and subgenotypes of Cryptosporidium in 7 human and 15 cattle cases of sporadic cryptosporidiosis in rural western NSW during the period from November 2005 to January 2006. The species/genotype of isolates was determined by PCR sequence analysis of the 18S rRNA and C. parvum and C. hominis isolates were subgenotyped by sequence analysis of the GP60 gene. Fourteen of 15 cattle-derived isolates were identified as C. parvum and 1 as a C. bovis/C. parvum mixture. Of the human isolates, 4 were C. parvum and 3 were C. hominis. Two different subgenotypes were identified with the human C. hominis isolates and six different subgenotypes were identified within the C. parvum species from humans and cattle. All four of the C. parvum subtypes found in humans were also found in the cattle, indicating that zoonotic transmission may be an important contributor to sporadic human cases cryptosporidiosis in rural NSW.
- Subject
- Cryptosporidium; genotyping; 18S rRNA; GP60; subtypes; zoonotic transmission
- Identifier
- http://hdl.handle.net/1959.13/41554
- Identifier
- uon:4867
- Identifier
- ISSN:0014-4894
- Language
- eng
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